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This article highlights the importance of diagnosing and treating elevated remnant lipoprotein cholesterol(RLP-c) in Non-HDL-c goal attainment in postmenopausal women.NCEP-ATP3 guidelines  consider RLP an "Emerging Lipid Risk Factor"and that in individuals with high serum triglycerides elevated RLP should be reduced in addition to the lowering of LDL-c.Nearly,at the same time(Atherosclerosis.2001) Dr.Judith McNamara and collegues found in the Framingham Heart Study ,which included 839 postmenopausal women, that RLP cholesterol (RLP-c)was an independent cardiovascular disease(CVD) risk factor in women.Elevated RLP-c in the fasting state which includes VLDL3-c and IDL-c is an independent CVD risk factor in postmenopausal women and is easily and reliably measured by Vertical Auto Profile.Elevated RLP-c can be reduced with niacin,fibrates,statins and omega 3 fatty acids and not only LDL-c but more importantly also Non-HDL-c goals in postmenopausal women can be achieved.

Thanks JR.  Great points.  Ironically in this lipidology specialty - remnant risk is largely ignored.  These TG rich remnants (VLDL3+IDL) are very high risk.  We find in 30-70% of people with normal serum TG's - high risk remnants can be directly measured. 

When looking at NHDLc and/or ApoB, oftentimes the LDL will be at goal, however the NHDLc and/or ApoB will be elevated due to remnant contribution.  Easy to identify and easy to target when you measure it directly rather than ldlc and ldlp calculations.  Thanks for pointing out this large unmet need.