2011 NLA Scientific Sessions

In his presentation, Dr Westman sought to dispel some "myths" and answer criticisms about the low-carbohydrate (low-carb) diet. He maintains that someone in a wheelchair can lose weight, even if they do not exercise, just by changing their diet. more

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According to Dr. Chapman, there are a number of therapeutic agents on the horizon that normalize levels of Apolipoprotein A-I (ApoA-I) and high-density lipoprotein cholesterol (HDL-C) for the acute and/or chronic treatment of patients at high cardiometabolic risk.

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It is not universally acknowledged that the relationship between high-density lipoprotein cholesterol (HDL-C) and coronary heart disease (CHD) risk is truly causal, and that targeting HDL-C levels automatically reduces risk.

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Individuals with chronic kidney disease (CKD) have raised levels of triglycerides and decreased levels of high-density lipoprotein cholesterol (HDL-C), as well as elevations in low-density lipoprotein cholesterol (LDL-C).

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All major dietary guidelines, including those of the Institute of Medicine (IOM), the American Dietetic Association (ADA), and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), all recommend 25-30% calories come from fat, i.e., a low-fat diet.

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Severe statin myopathy is usually defined as severe muscle damage with damage to another organ, such as a kidney, and creatinine kinase (CK) ≥10 x upper limit of normal (ULN). However, some severely affected patients have serum CK <10 x ULN. Of 166 patients with severe statin myopathy... more

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At least 95% of people with type-2 diabetes are insulin resistant. In the adipose tissue, insulin-resistant cells release fatty acids, increasing fatty acid flux to the liver resulting in transformation of the excess into triglycerides (TG)

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Dr Foody focused on the unintended consequences of formulary changes and the potentially harmful effects, with respect to providing evidence-based care or meeting therapeutic goals. She noted that in the United Kingdom (UK), forced switching of high-dose to low-dose statin resulted in higher rates... more

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In the Keynote Presentation of the 7th Annual Scientific Sessions, Dr Cohen reviewed what "simple" genetics can tell us about coronary heart disease (CHD).

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Prof. Barter reviews some recent trials with fibrates, statins, and niacin that he believes should have an impact on current clinical practice.

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