Use of Lipoprotein(a) in Clinical Practice: A Biomarker Whose Time Has Come.

Don P. Wilson, MD, Terry A. Jacobson, MD, Peter H. Jones, MD, Marlys L. Koschinsky, PhD, Catherine J. McNeal, MD, PhD, Børge G. Nordestgaard, MD, DMSc, Carl E. Orringer, MD

 

Highlights:

• Causal association between high lipoprotein(a) [Lp(a)] and atherosclerotic cardiovascular disease–related events and mortality.
• Laboratory methods and population-based considerations for Lp(a) cut points.
• When to measure Lp(a) in adults and youth.
• Treatment implications in primary and secondary prevention.