Enduring Internet Activity
Pediatrics
1.25 CME / CE Credits
The Child with Extreme LDL-C
Identifying HoFH Before Irreversible Disease
August 31, 2026 – August 31, 2027
Available now
1.25 credits
CME / CE for the healthcare team
Claim credit by August 31, 2027
1.25
CME / CE Credits
6
Learning Objectives
4
Expert Faculty
Enduring
Activity Type
Program Overview
HoFH remains chronically underdiagnosed
Despite the availability of highly effective therapies and established pediatric screening guidelines, HoFH remains chronically underdiagnosed, often because primary care pediatricians, the clinicians most likely to first encounter these children, lack the clinical confidence to distinguish extreme LDL elevations from other causes, initiate the appropriate diagnostic workup, and recognize when urgent specialty referral is warranted.
The activity guides learners through the full continuum of HoFH care in pediatric practice, from recognition of clinical and laboratory red flags, through screening and confirmation of diagnosis, to an evidence-based understanding of management strategies ranging from statins and PCSK9 inhibitors to lipid apheresis. The series culminates with practical guidance on referral decision-making and long-term, multidisciplinary management for children and families living with this condition.
Target Audience
This activity was designed for pediatric clinicians.
Physicians (MD/DO)
NPs
PAs
RNs
Pharmacists
Educational Objectives
What you’ll be able to do
Upon successful completion, participants should be better able to:
1
Identify clinical and laboratory findings that may indicate Homozygous Familial Hypercholesterolemia (HoFH) in pediatric patients.
2
Apply current pediatric lipid screening recommendations and diagnostic approaches to identify children at risk for HoFH.
3
Describe current and emerging management strategies for pediatric patients with HoFH.
4
Recognize clinical scenarios and LDL-C thresholds that warrant referral to a lipid specialist for further evaluation and management.
5
Discuss long-term management considerations and multidisciplinary care strategies for children and adolescents living with HoFH.
6
Discuss strategies to improve the knowledge, skills or performance of the healthcare team.
Faculty
Faculty, planners & reviewers

Ann Liebeskind
MD, FNLA, FAAP

Nivedita Patni
MD

Suzanne Shugg
DNP, CLS, FNLA

Justin Zachariah
MD
Individual financial disclosures are listed under Accreditation & Disclosures below.
Accreditation & Disclosures
The details, on demand
How to earn credit
Statements of credit will be awarded based on the participant’s attendance and submission of the activity evaluation form. Partial credit may be awarded for ACPE credit. A statement of credit will be available upon completion of an online evaluation/claimed credit form at the end of the activity. The deadline to claim credit is August 31, 2027.
Questions related to this content should be sent to cme@lipid.org.
Credit designation
CME/CE credit provided by the National Lipid Association
In support of improving patient care, this activity has been planned and implemented by the National Lipid Association. The National Lipid Association is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Credit Designation Statement
The National Lipid Association designates this live internet activity for a maximum of 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity
Physician Assistants
NCCPA accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.

Pharmacist Accreditation Statement
Universal Activity Number UAN JA0007192-0000-26-030-H01-P (Knowledge)
This Activity has been approved for 1.25 contact hour(s) (0.125 CEUs) of the Accreditation Council for Pharmacy Education
Nursing
The maximum number of hours awarded for this CE activity is 1.25 contact hours.
AMERICAN ACADEMY OF PEDIATRICS
This continuing medical education activity has been reviewed by the American Academy of Pediatrics and is acceptable for a maximum of 1.25 AAP credits. These credits can be applied toward the AAP CME/CPD Award available to Fellows and Candidate Members of the American Academy of Pediatrics.
Faculty disclosures
| Ann Liebeskind, MD, FNLA, FAAP | Has nothing to disclose. |
| Nivedita Patni, MD | Chiesi — Speaker |
| Suzanne Shugg, DNP, CLS, FNLA | Regeneron — Speaker |
| Justin Zachariah, MD | NIH R01 — Grant Recipient |
| NLA Staff | Has nothing to disclose. |
It is the policy of NLA to ensure independence, balance, objectivity, scientific rigor, and integrity in all of its continuing education activities. Planners, faculty, reviewers, and staff have disclosed any financial relationships with commercial interests as defined by the ACCME.
Unlabeled use, disclaimer & permissions
Disclosure of unlabeled use and investigational products
This educational activity may include discussion of uses of agents that are investigational and/or unapproved by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
This course is designed solely to provide the healthcare professional with information to assist in his/her practice and professional development and is not to be considered a diagnostic tool to replace professional advice or treatment. The course serves as a general guide to the healthcare professional, and therefore, cannot be considered as giving legal, nursing, medical, or other professional advice in specific cases. The NLA specifically disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through reader’s misunderstanding of content.
Permissions
The National Lipid Association acknowledges that permissions have been obtained for use of all copyrighted materials, including graphs, tables, pictures, and charts printed in this activity syllabus. Permissions have also been obtained from identifiable patients in photographs and other images, consistent with the DHHS HIPAA regulations for individual privacy.
Commercial support
This activity is supported by an independent educational grant from Regeneron Pharmaceuticals Inc.
Earn your 1.25 credits
Available on demand through August 31, 2027.