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The results of the HPS2-THRIVE study were released in the New England Journal of Medicine on July 17, 2014. Also, appearing in the same edition was a special correspondence from the AIM HIGH investigators concerning further analysis of adverse events, and an editorial addressing both of these publications.

Statins play a critical role in reducing the risk of heart disease. Not only are the benefits greatly appreciated by both physicians and patients, the majority of statins are also well tolerated. Despite this, many patients discontinue statin therapy against medical advice, oftentimes without notifying their doctors. For this reason, the National Lipid Association embarked on a study that used internet surveys to determine why patients discontinue their statins.