The lipid hypothesis states that elevated plasma cholesterol, more specifically, LDL cholesterol, has a causal role in the development of coronary heart disease and other cardiovascular diseases. This hypothesis has been debated for over 150 years. Cholesterol was first discovered in bile and in the gallstones by Poulletier de la Salle in 1769 and rediscovered by Michel Eugene Chevreul in 1815. The latter coined the name “cholesterine” which was shown to be present in bilestones.
Article By:
Antonio M. Gotto Jr., MD, DPhil, FNLA
President, National Lipid Association, 2019-2020
Last Updated: Tuesday, 24-May-2022 12:30:00 EDT
Regeneron Pharmaceuticals, Inc. announced positive results from a Phase 3 trial evaluating Evkeeza® (evinacumab) in children aged 5 to 11 with homozygous familial hypercholesterolemia (HoFH). The trial met its primary endpoint, showing children who added investigational evinacumab to other lipid-lowering therapies reduced their low-density lipoprotein-cholesterol (LDL-C) by an average of 48% at week 24 of the study. Anne C.
Last Updated: Monday, 11-Apr-2022 18:30:00 EDT
Kowa Research Institute, Inc. has announced the decision to not continue its Phase 3 PROMINENT study. Read the press release. Kowa has indicated that full data will be shared at a future conference.
Last Updated: Thursday, 31-Mar-2022 21:15:00 EDT
Be sure to read the latest JCL Roundtable featuring Lauren Williams, RDN, Lynne T. Braun, PhD, CNP, FNLA, Joseph J. Saseen, PharmD, FNLA, and John R. Guyton, MD, FNLA discussing the importance of the lipidology team.
Abstract
Thank you for participating in the 21 Day Challenge. Below please find your opportunity to reflect on today's activity. Note: Chapter and Reflection are the only mandatory fields, though the NLA hopes to collect participant demographic data for improvement of DEI within our organization.
This page was last updated: Mar 13, 2022
Thank you for participating in the 21 Day Challenge. Below please find your opportunity to reflect on today's activity. Note: Chapter and Reflection are the only mandatory fields, though the NLA hopes to collect participant demographic data for improvement of DEI within our organization.
This page was last updated: Mar 12, 2022
Thank you for participating in the 21 Day Challenge. Below please find your opportunity to reflect on today's activity. Note: Chapter and Reflection are the only mandatory fields, though the NLA hopes to collect participant demographic data for improvement of DEI within our organization.
This page was last updated: Mar 12, 2022