Most coronary heart disease occurs in those over the age of 65.1 Statins reduce cardiovascular morbidity and mortality in both primary and secondary prevention.
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While there is evidence for atherosclerotic cardiovascular risk reduction with statins in both primary and secondary prevention in older patients, there is a higher incidence of associated muscle symptoms and discontinuation because of those symptoms.1-3 Thus, consideration of the risk-benefit ratio of statins in older patients is recommended.4
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Atherosclerosis is a lipid-driven disorder and the main underlying cause of cardiovascular disease (CVD).1 Microbiology has long been a critical focal area of medicine in terms of the effect of bacterial organisms on health and disease. What is the contemporary view of the relationship between these two aspects of clinical medicine?
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I am sure that you, like me, often are puzzled when other healthcare providers ask if we should use statins in older or more mature patients. On an intuitive level, I wonder why this needs to be asked. Older patients are much more likely to have developed atherosclerotic disease and, as a result, suffer from myocardial infarction (MI), stroke, the need for revascularization, and death.
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Dr. Barter’s perspective in the accompanying editorial is summarized in the last sentence of his article: “Given these facts, it is difficult to argue against the proposition that, unless contraindicated, all people older than 65 should receive a statin, regardless of the presence or absence of risk factors other than older age. Such action has the potential to substantially reduce morbidity in the elderly.”
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Introduction
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You can’t miss it. At the mall, at the gym, in your office, the percentage of older Americans is growing. By the year 2020 there will be more than 55 million Americans older than 65.1 Medically, we know not to treat kids just like “little adults” and we should have this same respect for differences in the management of older adults. This should apply to both our pharmaceutical and nutritional recommendations.
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The editors of LipidSpin wish to acknowledge the publication and update of the United States Preventive Services Task Force (USPSTF) report on Statin Use for the Primary Prevention of Cardiovascular Disease in Adults.1 It is relevant to this issue of LipidSpin, which is dedicated to the topic of lipids and aging. Please see the report released online in the November 15, 2016, edition of the Journal of the American Medical Association (JAMA).
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I love the theme of this edition of the LipidSpin, Lipids & Aging. When you read through the various articles, you will find outstanding discussions regarding the many aspects of treating older patients. Whenever I treat older patients with dyslipidemia, I always start by considering the overall risks versus benefits of statin therapy. Then I proceed to other aspects and considerations of providing patient-centered care.
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I am honored and humbled to be serving as president of the Midwest Lipid Association (MWLA). The Midwest Chapter did a tremendous job preparing for this edition of the LipidSpin, which focuses on lipids and aging. The contributions from our NLA colleagues within the Midwest Chapter are outstanding, and this promises to be an excellent issue.