Spring 2024

Guest Editorial: Lipid Management in Patients with Chronic Inflammatory Conditions

Introduction Immune system activation – i.e., systemic inflammation, plays an essential role in all stages of atherosclerosis, from the development of the fatty streak to acute plaque rupture.1 Autoimmune diseases are common, with a prevalence of up to 8% of the United States (US) adult... more

EBM Tools for Practice: The Thyroid-Lipid Axis: Implications for Atherosclerosis and Beyond

Dyslipidemia frequently presents in individuals with thyroid dysfunction, attributed to the influence of thyroid hormones on various key metabolic pathways, thereby contributing to an elevated cardiovascular (CV) risk.1 In this discussion, we delve into the intricate connection between thyroid... more

Lipid Luminations: Lipid Management in Chronic Kidney Disease

Introduction Chronic kidney disease (CKD) ranks among the top five causes of global mortality, affecting approximately 35.5 million people in the United States (US).1,2 Despite being preventable and treatable, the prevalence of CKD and related mortality are on the rise, making it an important... more

Specialty Corner: Lipid Management in Pregnancy and Lactation

Introduction Normal pregnancy is characterized by physiologic increases in maternal levels of cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). These lipoproteins are taken up by the placenta and support optimal fetal... more

Practical Pearls: Dyslipidemia Management in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Key points MASLD is a risk factor for atherosclerotic cardiovascular disease and is associated with cardiometabolic risk factors, such as obesity (adiposopathy), hypertension, insulin resistance, diabetes and dyslipidemia. The cornerstone of MASLD management is aggressive treatment of risk... more