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DS: Thank you for joining me today Fran. First, I would like to introduce myself and then you to the LipidSpin readers. I am Dan Soffer, a full-time internist, clinical lipidologist and educator at the University of Pennsylvania. I am also President-Elect of the Northeast Lipid Association (NELA) and co-editor of LipidSpin.

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FRAN BURKE MS, RD

University of Pennsylvania Health System
Preventive Cardiology Radnor and Perelman Center for Advanced Medicine
Philadelphia, PA

Moderator: DANIEL SOFFER, MD, FACP, FNLA

Internal Medicine/Clinical Lipidology
University of Pennsylvania Health System
Philadelphia, PA
Diplomate, American Board of Clinical Lipidology

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After an article by Drs. Peter H. Jones and James M. McKenney in LipidSpin one year ago1 that reported on emerging therapeutics in clinical lipidology, it is still a very exciting time for the development of novel treatments for dyslipidemic patients.

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MARINA CUCHEL, MD, PhD

Research Associate Professor of Medicine
Division of Translational Medicine and Human Genetics
University of Pennsylvania
Philadelphia, PA

ARCHNA BAJAJ, MD, MSCE

Post-doctoral Fellow
Division of Translational Medicine and Human Genetics
University of Pennsylvania
Philadelphia, PA

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Introduction

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BRUCE A. WARDEN, PharmD, BCPS-AQ CARDIOLOGY

Center for Preventive Cardiology
Knight Cardiovascular Institute
Oregon Health & Science University
Portland, OR

P. BARTON DUELL, MD, FNLA

Center for Preventive Cardiology
Knight Cardiovascular Institute
Oregon Health & Science University
Portland, OR

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Abstract

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DIPIKA JAIRAM GOPAL, MD

Cardiology Fellow Physician
University of Pennsylvania
Philadelphia, PA

DANIEL E. SOFFER, MD, FACP, FNLA

Internal Medicine/Clinical Lipidology
University of Pennsylvania Health System
Philadelphia, PA
Diplomate, American Board of Clinical Lipidology

DANIELLE FORTUNA, MD

Hepatic Pathology Fellow
University of Pennsylvania
Philadelphia, PA

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Peripheral artery disease (PAD) is a common manifestation of systemic atherosclerosis affecting 20% of Americans over the age of 801 and over 200 million people worldwide.2 As well as being common, it also carries high mortality and morbidity; and yet, patients with PAD are overlooked on multiple levels. Many go unrecognized in clinical practice.

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JEREMY VAN'T HOF, MD

Cardiovascular Division
University of Minnesota
Minneapolis, MN

DANIEL DUPREZ, MD, PhD, FNLA

Cardiovascular Division
University of Minnesota
Minneapolis, MN

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A 73-year-old woman with coronary and peripheral arterial disease with hyperlipidemia was referred for a lipidology consult because of elevated liver function tests (LFTs) while on rosuvastatin. Aspartate amino transferase (AST) rose from a baseline of 26 to 120 and alanine amino transferase (ALT) from 15 to 132. She did not drink alcohol nor take other hepato-toxic pharmaceuticals.

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JAMES TRIPPI, MD, FACC, FNLA

Complex Cholesterol Center
St. Vincent Health
Indianapolis, INLFTs

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In 2009, a 75-year-old Tsimane man and his wife awoke and went out into the rain forest around their home in the Amazonian lowlands of Bolivia to collect jajata, a palm like plant used to make roofing. Walking home in the afternoon, he collapsed to the ground, unconscious. His wife shook him and after a few minutes he regained consciousness. He complained of chest pain radiating down his left arm. He was having trouble breathing but managed to stand and walk home.

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CHRIS J. ROWAN, MD, FACC

Medical Director for Research
Renown Institute for Heart and Vascular Health, Healthy Nevada Project
University of Nevada School of Medicine
Reno, NV

GREGORY S. THOMAS, MD, MPH, FACC, MASNC

Medical Director
Cardiovascular Program Development
MemorialCare Heart and Vascular Institute
Clinical Professor
Division of Cardiology
University of California, Irvine
Fountain Valley, CA

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Introduction
Coronary artery calcium scoring (CACS) was first introduced in the early 1990s as a method for early coronary artery disease (CAD) detection. Since then, there have been significant advancements in CACS from a technological standpoint, but more importantly, continuing compilation of supportive data has led to more widespread use, but certainly not universal acceptance.

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MINAKSHI BISWAS, MD

Fellow in Cardiovascular Medicine
University of Colorado

SHU CHANG, MD

Fellow - Cardiovascular Disease
University of Colorado

EDWARD A. GILL, MD, FNLA

Director of Interventional Echocardiography
Professor of Medicine
Division of Cardiology
University of Colorado School of Medicine, Anschutz
Diplomate, American Board of Clinical Lipidology

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Those born with familial hypercholesterolemia (FH) know better than anyone else that they have a family history of early heart disease.

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KATHERINE WILEMON

Founder and CEO
FH Foundation
Pasadena, CA

JOSHUA W. KNOWLES, MD, PhD

Chief Medical Advisor
FH Foundation
Assistant Professor of Cardiovascular Medicine
Stanford University Medical Center
Stanford, CA

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