As a professional organization, the National Lipid Association's mission has been to reduce the morbidity and mortality from cardiovascular disease by increasing the understanding of the pathophysiology, and detection and optimal treatment of lipid disorders. Developing patient registries is crucial to this mission by pooling patient data concerning more rare dyslipidemias so that epidemiologic and/or clinical research can be more focused.
The Foundation of the NLA constantly strives to support research, medical education and community outreach activities, particularly those that fall within our primary areas of focus for grant funding: children, genetic disorders, Familial Hypercholesterolemia (FH), primordial prevention, and underserved populations.
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Randy Burden, PharmD, often traveled to the eight northern Pueblo tribes in New Mexico as part of his job with the U.S. Indian Health Service cardiovascular risk reduction program. At each site visit, he became engulfed in addressing lipid disorders, diabetes, the metabolic syndrome, and blood pressure problems in his patient population.
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Multiple observational studies have found an inverse relationship between highdensity lipoprotein cholesterol (HDL-C) levels and cardiovascular disease (CVD).1-3 The cumulative mechanism(s) by which HDL-C is associated with reduction in CVD is/are intricate and multifactorial.2 Pharmacologic approaches to increase HDL-C have been successful, but the studies assessing the cardio protective effect(s) of these interventions often has been conflicting and is debatable.4
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A 37-year-old patient was referred to our lipid clinic from his primary care provider. A basic lipid panel revealed: total cholesterol (TC) 715 mg/dL, triglyceride (TG) 901 mg/dL; HDL-C 45 mg/dL, Lipoprotein(a) [Lp(a)] mass was elevated (44 mg/dL); Lp(a)- cholesterol levels were not measured. The patient, who was generally very healthy, had not seen a physician for several years. He presented with bilateral palmar xanthomas (see Photo 1).
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She is sitting in your office waiting room. That fat, hairy woman for whom you can pretty much guarantee her chief complaint —amenorrhea, abnormal hair growth or knee pain. You know the Pandora’s Box of diagnoses she really should be worried about: diabetes, hyperlipidemia, endometrial cancer. So many problems, so little time, so little compensation.
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In keeping with the theme of this issue of Lipid Spin, I have chosen waist circumference as the physical finding that can lead us to so much more in terms of atherosclerosis risk assessment. As we know, nearly 80 million Americans have metabolic syndrome, and enlarged waist circumference is the physical expression of this syndrome.1 To borrow a phrase from my good friend and mentor, Tom Dayspring, metabolic syndrome patients are diabetics in-training.
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Physical chemistry is, in part, the study of macroscopic and particulate phenomena in terms of laws and concepts of physics, and it can include the physical concepts determining motion, energy, force, time, thermodynamics, light and equilibrium. Physical chemistry, in contrast to chemical physics, is a macroscopic science, because its concepts are relevant to bulk scales rather than molecular and/or atomic scales.
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This issue of Lipid Spin has a theme of physical findings. One of my colleagues e-mailed me and said I was such an evidence-based guy that he applauded me for choosing a topic that was not evidence based.
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Chances are that each of us has and takes care of patients from Southeast Asia. This ethnic group is growing significantly in the United States. According to 2010 census data, while the U.S. population grew almost 9.7% between 2000 and 2010, the Asian population alone increased by more than four times that rate—by 43% in that 10-year period.1
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Specialist in Clinical Hypertension
Associate Medical Director, Disease Management and Adult
Primary Care – Colorado Springs Health Partners
Adjunct Associate Professor of Family Medicine and Community
Preceptor – University of Colorado
Department of Family Medicine
Colorado Springs, CO
Diplomate, American Board of Clinical Lipidology


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